Opens in a new tab
Treatment guide

Could PRP help?

Platelet-rich plasma (PRP) uses concentrated platelets from your own blood to help manage joint and tendon pain. Discover how it works, what to expect and whether it could support your return to more comfortable movement.
Could PRP help?

PRP at a glance

A clinician holding a tube of separated platelet-rich plasma

Platelet-rich plasma (PRP) is an injection made from your own blood, used to help manage joint pain and certain tendon problems.

  • Made from your own blood. A sample is taken and processed to concentrate platelets, which contain proteins involved in the body’s repair response.
  • Treats the affected area. The concentrated platelets are injected into the joint or tendon area, usually during the same appointment.
  • Aims to ease pain and improve movement. Your clinician will assess whether PRP is suitable for your condition.
  • Improvement takes time. Benefits may develop over several weeks. Temporary soreness can occur, and results vary.
    Part of your recovery plan.

PRP should sit alongside appropriate exercise and rehabilitation. It is not a proven way to regrow cartilage or reverse arthritis, and it does not contain stem cells, although PRP prepared correctly has a mix of cells within it that can help further.

How PRP works

PRP uses concentrated platelets from your own blood to deliver growth factors to the treatment area. The aim is to ease symptoms and improve movement. Here’s how the process works.

What do the platelets do?

Platelets help blood clot, but they also release chemical messages involved in healing. PRP delivers a concentrated amount of these platelets to the treatment area.

Where can it help?

PRP has shown benefits for some people with mild to moderate knee osteoarthritis and certain persistent tendon problems. Evidence varies between conditions, so an accurate diagnosis matters.

Why isn’t all PRP the same?

Preparation methods produce different platelet concentrations and amounts of other blood cells. Your clinician should explain the preparation they use and why it suits your treatment.

When might I notice a difference?

Improvement can take several weeks. Temporary soreness may occur after the injection, and some people do not experience a meaningful benefit.

Will regenerate my joint?

PRP has not been established as a way to regrow worn cartilage or reverse osteoarthritis. The treatment goal is better comfort and function, but it does work with your bodys own biology.

How many injections will I need?

Your clinician may recommend one injection or a course, depending on your condition and treatment plan. Ask when your progress will be reviewed.

When will I notice results?

PRP works gradually. Improvement may take several weeks, and results vary depending on your condition and treatment plan. This is a guide rather than a fixed timetable.

First few days

The treated area may feel sore or swollen. Follow your clinician’s advice on pain relief, rest and gentle movement.

Weeks 1 to 2

You may notice little change at this stage. Early soreness should begin to settle, although it can last longer for some people.

Weeks 3 to 6

Some people begin to notice less pain or easier movement. Others take longer. Follow your rehabilitation plan and increase activity gradually.

Weeks 6 to 12

This can be a useful time to review progress. Look for practical changes, such as walking more comfortably, managing stairs or finding exercises easier.

Months 3 to 6

Benefits may continue to develop or settle into a steadier pattern. If improvement is limited, discuss your progress and other options with your clinician.

Beyond six months

Some people experience longer-lasting relief; others find symptoms return. Further treatment should follow a review of your symptoms and response.

Is PRP right for you?

PRP may be an option for some people with knee osteoarthritis or persistent tendon problems. Your clinician will assess your diagnosis, previous treatment and overall health to help you decide.

Pain that keeps getting in the way

Symptoms continue to affect everyday life despite an appropriate course of exercise, physiotherapy or other treatment.

A condition that may respond

PRP has shown benefits in mild to moderate knee osteoarthritis and certain tendon problems. Evidence differs between conditions and body areas.

A goal of moving more comfortably

You want to make activities such as walking, working or exercising easier, with treatment supporting a wider rehabilitation plan.

Time to work on recovery

Benefits can take several weeks to develop. Following your exercise plan and attending reviews are important parts of treatment.

When other options may be more helpful

Advanced arthritis or significant changes in joint shape may limit the benefit. Your clinician can explain alternatives, including when a surgical opinion is appropriate.

Checks before treatment

An active infection or certain blood and platelet disorders may make PRP unsuitable. Tell your clinician about your medical conditions and medicines before treatment.

PRP FAQ's and fast facts

PRP can be described in so many ways online; here we cover the main points you need to know.

Is PRP safe?

PRP uses your own blood, which reduces the risk of allergic reaction, and whole-body side effects are uncommon. As with any injection there are small risks, such as temporary soreness, a short-term flare or, rarely, infection. Your clinician should review your medical history and medicines, including blood thinners, first.

What is PRP treatment, and what can it help with?

Platelet-rich plasma (PRP) is made by concentrating platelets from your own blood and injecting them into the area being treated. It may help some people with knee osteoarthritis or certain persistent tendon problems. The evidence varies by condition, so your clinician should explain the likely benefits for you.

Are PRP injections painful?

You may feel a brief sting during the blood sample and discomfort or pressure during the injection. The treated area can feel more sore afterwards, sometimes for several days. Your clinician will explain what to expect and how to manage discomfort.

How long does PRP take to work, and how long does it last?

Improvement usually develops gradually over several weeks. Some people experience relief lasting months, while others notice little benefit. There is no guaranteed timetable or duration. Your clinician should arrange a review to assess changes in pain, movement and everyday activity.

How many PRP injections will I need?

Some treatment plans involve one injection; others use a course. The number and spacing depend on your condition, the PRP preparation and your response. Before starting, ask how many appointments are proposed, what the full course costs and when progress will be reviewed.

How much blood will need to be taken

This again can vary depending on what you need. PRP is used in aesthetics, for example, or even hair restoration, and it tends to require smaller blood samples because those procedures need fewer platelets. For an arthritic large joint, don’t be alarmed if your clinicians take 80 mL of blood. This takes around 2 – 3 minutes. This gives a much higher platelet count and stronger biological injection.

What are the risks of PRP injections?

Temporary pain, swelling and bruising can occur. Less common complications include infection, bleeding and injury to nearby tissues. Using your own blood does not make treatment risk-free. Seek urgent medical advice if you develop increasing pain with heat, redness, fever or feeling unwell.

Can I exercise or go to work after PRP?

This depends on the area treated and how physically demanding your work or exercise is. You may need to reduce strenuous activity initially, then build up gradually with a rehabilitation plan. Ask your clinician about work, driving and sport before your appointment.

Should I stop any medicines before PRP?

Tell your clinician about all medicines and supplements you take. They may recommend changes to anti-inflammatory medicines such as ibuprofen around treatment, but advice varies. Do not stop prescribed aspirin, blood thinners or other medicines without agreement from the clinician responsible for them – but do tell your clinicians carrying out the PRP procedure.

How much does PRP treatment cost, and will insurance cover it?

Prices vary by clinic, treatment area and number of injections. Ask whether the quoted price includes assessment, ultrasound guidance, follow-up and rehabilitation. Insurance coverage also varies, so confirm approval with your insurer before booking.

The PRP procedure: what to expect

Most appointments last around 30 to 45 minutes in a clinic room. Afterwards you can usually walk out and most people drive themselves home. This short video shows how PRP is prepared.